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KMID : 0358419960390040785
Korean Journal of Obstetrics and Gynecology
1996 Volume.39 No. 4 p.785 ~ p.789
Successful Surrogate Pregnancy after IVF-ET in Patient of Congenital Absence of Vagina
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Abstract
A case of successful pregnancy and delivery, after in vitro fertilization and embryo transfer9IVF-ET0 through gestational surrogate program, in patients with congenital absence of vagina is reported. The patient who was married after
vaginoplasty(McIndoe operation) and only rudimentary uterus but normally functioning both ovaries which were confirmed by laparoscopy. Patient's younger sister was a completely healthy mother of two and willing to act as a surrogate gestational
carrier
for her sister. GnRH-a(buserelin), estradiol valerate, hMG and hCG were used for synchronization of the reproductive cycles of the two sisters, controlled artificial preparation of the endometrium and IVF-ET. To maintain pregnancy in gestational
surrogate carrier woman, exogenous estradiol and progesterone was administered until placental autonomy was established. A girl(2,950g) was delivered at 41 weeks of gestation and is doing well.
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